周晓明

姓名：周晓明

职称：教授

联系电话：62604169

电子邮箱：xmzhou@bio.ecnu.edu.cn

通讯地址：华东师范大学脑功能基因组学教育部重点实验室

研究方向：听觉神经生物学

个人简介：

主要以听觉系统为模型，从个体行为、系统、神经网络及突触分子等不同水平和层次研究脑感觉、认知及可塑性机制。

代表性论文（选自50篇论文）：

1. Zhang Y, Zhu M, Sun Y, Tang B, Zhang G, An P, Cheng Y, Shan Y, Merzenich MM, Zhou X. Environmental noise degrades hippocampus-related learning and memory. Proc Natl Acad Sci USA (In press, accepted on Oct.21, 2020).

2. Cheng Y, Zhang Y, Wang F, Jia G, Zhou J, Shan Y, Sun X, Yu L, Merzenich MM, Recanzone GH, Yang L, Zhou X (2020) Reversal of age-related changes in cortical sound-azimuth selectivity with training. Cerebral Cortex. 30:1768-1778.

3. Liu X, Wei F, Cheng Y, Zhang Y, Jia G, Zhou J, Zhu M, Shan Y, Sun X, Yu L, Merzenich MM, Lurie D, Zheng Q, Zhou X (2019) Auditory training reverses lead (Pb)-toxicity-induced changes in sound-azimuth selectivity of cortical neurons. Cerebral Cortex. 29:3294-3304.

4. Cheng Y, Jia G, Zhang Y, Hao H, Shan Y, Yu L, Sun X, Zheng Q, Kraus N, Merzenich MM, Zhou X (2017) Positive impacts of early auditory training on cortical processing at an older age. Proc Natl Acad Sci USA 114:6364-6369.

5. Zhu X, Liu X, Wei F, Wang F, Merzenich MM, Schreiner CE, Sun X, Zhou X (2016) Perceptual training restores impaired cortical temporal processing due to lead exposure. Cerebral Cortex. 26:334-345.

6. Zhou X, Lu YF, Darling RD, Simpson KL, Zhu X, Wang F, Yu L, Sun X, Merzenich MM, Lin RC (2015) Behavioral training reverses global cortical network dysfunction induced by perinatal antidepressant exposure. Proc Natl Acad Sci USA 112:2233-2238.

7. Zhu X, Wang F, Hu H, Sun X, Kilgard MP, Merzenich MM, Zhou X (2014) Environmental acoustic enrichment promotes recovery from developmentally degraded auditory cortical processing. Journal of Neuroscience. 34:5406-5415.

8. Zhang Y, Zhao Y, Zhu X, Sun X, Zhou X (2013) Refining cortical representation of sound azimuths by auditory discrimination training. Journal of Neuroscience. 33:9693-9698.

9. Zhou X, Merzenich MM (2012) Environmental noise exposure degrades normal listening processes. Nature Communications 10.1038/ncomms1849, 3:843.

10. Zhou X, Panizzutti R, de Villers-Sidani É, Madeira C, Merzenich MM (2011) Natural restoration of critical period plasticity in the juvenile and adult primary auditory cortex. Journal of Neuroscience. 31:5625-5634.

11. Zhou X, de Villers-Sidani É, Panizzutti R, Merzenich MM (2010) Successive-signal biasing for a learned sound sequence. Proc Natl Acad Sci USA 107:14839-14844.

12. Zhou X, Merzenich MM (2009) Developmentally degraded cortical temporal processing restored by training. Nature Neuroscience.12:26-28.

13. Zhou X, Merzenich MM (2008) Enduring effects of early structured noise exposure on temporal modulation in the primary auditory cortex. Proc Natl Acad Sci USA 105:4423-4428.

14. Zhou X, Nagarajan N, Mossop BJ, Merzenich MM (2008) Influences of un-modulated acoustic inputs on functional maturation and critical-period plasticity of the primary auditory cortex. Neuroscience.154:390-396.

15. Zhou X, Merzenich MM (2007) Intensive training in adults refines A1 representations degraded in an early postnatal critical period. Proc Natl Acad Sci USA 104:15935-15940.  

16. Zhou X, Jen PH (2007) Corticofugal modulation of multi-parametric auditory selectivity in the midbrain of the big brown bat. Journal of Neurophysiology. 98:2509-2516.

17. Zhou X, Sun XD (2006) Sound Azimuth selectivity of inferior collicular neurons in juvenile bats, Myotis chinensis, NeuroReport. 17:1411-1415

18. Zhou X, Jen PH, Seburn KL, Frankel WN, Zheng QY (2006) Auditory brainstem responses in 10 inbred strains of mice. Brain Research. 1091:16-26.

19. Zhou X, Jen PH (2005) Corticofugal modulation of directional sensitivity in the midbrain of the big brown bat, Eptesicus fuscus. Hearing Research. 203:201-215.

20. Zhou X, Jen PH (2004) Azimuth-dependent recovery cycle affects directional selectivity of bat inferior collicular neurons determined with sound pulses within a pulse train. Brain Research. 1019:281-288

21. Jen PH, Zhou X (2003) Corticofugal modulation of amplitude domain processing in the midbrain of the big brown bat, Eptesicus fuscus. Hearing Research. 184:91-106.

22. Zhou X, Jen PH (2003) The effect of bicuculline application on azimuth-dependent recovery cycle of inferior collicular neurons of the big brown bat, Eptesicus fuscus. Brain Research. 973:131-141.

23. Zhou X, Jen PH (2002) The role of GABAergic inhibition in shaping directional selectivity of bat inferior collicular neurons determined with temporally patterned pulse trains. Journal of Comparative Physiology. 188:815-826.

24. Zhou X, Jen PH (2002) The effect of sound duration on rate-intensity functions of inferior collicular neurons in the big brown bat, Eptesicus fuscus. Hearing Research. 166:124-135.

25. Jen PH, Zhou X, Zhang JP, Chen QC, Sun XD (2002) Brief and short-term corticofugal modulation of acoustic signal processing in the bat midbrain. Hearing Research. 168:196-207

26. Zhou X, Jen PH (2001) The effect of sound intensity on duration tuning characteristics of bat inferior collicular neurons. Journal of Comparative Physiology. 187:63-73.

27. Jen PH, Zhou X, Wu CH (2001) Temporally patterned sound pulse trains affect intensity and frequency sensitivity of inferior collicular neurons of the big brown bat, Eptesicus fuscus. Journal of Comparative Physiology. 187:605-616.

28. Zhou X, Jen PH (2000) Brief and short-term corticofugal modulation of subcortical auditory responses in the big brown bat, Eptesicus fuscus. Journal of Neurophysiology. 84:3083-3087.

29. Zhou X, Jen PH (2000) Corticofugal inhibition compresses all types of rate-intensity functions of inferior collicular neurons in the big brown bat. Brain Research. 881:62-68.

30. Zhou X, Jen PH (2000) Neural inhibition sharps spatial selectivity of bat inferior collicular neurons. Journal of Comparative Physiology. 186:389-398.

31. Jen PH, Zhou X (1999) Temporally patterned sound trains affect duration tuning characteristics of bat inferior collicular neurons. Journal of Comparative Physiology. 185:471-478.