| 姓名：尹大志 职称：青年研究员 联系电话：15216707963 电子邮箱：dzyin@psy.ecnu.edu.cn 通讯地址：上海市普陀区中山北路3663号老图书馆311室，200062 研究方向： 脑网络及其可塑性 |
个人简介： 尹大志，现任华东师范大学心理与认知科学学院紫江青年研究员，博士生导师。2014年6月毕业于华东师范大学物理系上海市磁共振重点实验室，获得理学博士学位。博士期间（2012年9月至2014年5月），在美国哥伦比亚大学精神病学系进行博士生联合培养（国家留学基金委公派）。2014年8月至2019年9月，在中国科学院神经科学研究所脑影像中心依次担任助理研究员、副研究员。曾入选“中国科学院青年创新促进会”，2018年获得“长三角神经科学青年科学家奖”和“赛诺菲-中国科学院上海生命科学研究院”优秀青年人才奖励基金，主要从事脑网络及其可塑性研究，特别关注动态脑网络方法学。相关研究成果以第一或通讯作者（含共同）已发表在Biological Psychiatry、Journal of Neuroscience、Journal of Clinical Endocrinology & Metabolism、Human Brain Mapping、American Journal of Neuroradiology等国际主流学术期刊上。主持了国家自然科学基金项目和中科院项目，参与了科技部和基金委等多项科研项目。 | |
主持的科研项目： 1. 国家自然科学基金青年项目, “静息态功能连接模式的动态重配及其应用研究”，31600869，2017/1-2019/12，20万元 2.中国科学院青年创新促进会资助基金, 2018/1-2021/12，80万元（20万/年） 3.中国科学院上海生命科学研究院优秀青年人才领域前沿项目, “一种联合多模态磁共振成像方法预测脑中风患者手功能转归”, 2014KIP206,已结题，2014/10-2016/9，15万元 | |
实验手段： | |
发表论文： 1. Su H, Liu Y, Yin D, Chen T, Li X, Zhong N, Jiang H, Wang J, Du J, Xiao K, Xu D, Zeljic K, Wang Z, Zhao M. Neuroplastic changes in resting-state functional connectivity after rTMS intervention for methamphetamine craving. Neuropharmacology. 2020; 175:108177 2.Lv Q, Lv Q, Yin D, Zhang C, Sun B, Voon V, Wang Z. Neuroanatomical Substrates and Predictors of Response to Capsulotomy in Intractable Obsessive-Compulsive Disorder. Biological psychiatry: Cognitive neuroscience and neuroimaging. 2020, In press 3.Yin D, Chen X, Zeljic K, Zhan Y, Shen X, Yan G, and Wang Z. A Graph Representation of Functional Diversity of Brain Regions. Brain and Behavior. 2019; e01358. 4.Fang F, Lai M, Huang J, Kang M, Ma M, Li K, Lian J, Wang Z, Yin D*, Wang Y*. Compensatory Hippocampal Connectivity in Young Adults with Early-Stage Type 2 Diabetes. The Journal of Clinical Endocrinology & Metabolism. 2019; 104:3025–3038. 5.Yin D, Zhang Z, Wang Z, Zeljic K, Lv Q, Cai D, Wang Y, Wang Z. Brain Map of Intrinsic Functional Flexibility in Anesthetized Monkeys and Awake Humans. Frontiers in Neuroscience. 2019, 13:174. 6.Li HF#, Yang L#, Yin D#, Chen WJ, Liu GL, Ni W, Wang N, Yu W, Wu ZY, Wang Z. Associations between neuroanatomical abnormality and motor symptoms in paroxysmal kinesigenic dyskinesia. Parkinsonism & Related Disorders. 2019; 62:134-140 7.Yin D#, Zhang C#, Lv Q, Chen X, Zeljic K, Gong H, Zhan S, Jin H, Wang Z, Sun B. Dissociable Frontostriatal Connectivity: Mechanism and Predictor of the Clinical Efficacy of Capsulotomy in Obsessive-Compulsive Disorder. Biological Psychiatry. 2018; 84:926-936. 8.Zhao Z, Wu J, Fan M, Yin D, Tang C, Gong J, Xu G, Gao X, Yu Q, Yang H, Sun L, Jia J. Altered intra- and inter-network functional coupling of resting-state networks associated with motor dysfunction in stroke. Human Brain Mapping. 2018; 39:3388-3397. 9.Zhao Z, Tang C, Yin D, Wu J, Gong J, Sun L, Jia J, Xu D, Fan M. Frequency-specific alterations of regional homogeneity in subcortical stroke patients with different outcomes in hand function. Human Brain Mapping. 2018; 39:4373-4384. 10.Zou Y, Zhao Z, Yin D, Fan M, Small M, Liu Z, Hilgetag CC, Kurths J. Brain anomaly networks uncover heterogeneous functional reorganization patterns after stroke. Neuroimage Clinical. 2018; 20:523-530. 11.Peng W, Mao L, Yin D, Sun W, Wang H, Zhang Q, Wang J, Chen C, Zeng M, Ding J, Wang X. Functional network changes in the hippocampus contribute to depressive symptoms in epilepsy. Seizure. 2018; 60:16-22. 12.Fang F, Zhan Y, Zhuo Y, Yin D, Li K, Wang Y. Brain atrophy in middle-aged subjects with Type 2 diabetes mellitus, with and without microvascular complications. Journal of Diabetes. 2018; 10:625-632. 13.Song Y, Li W, Meng S, Zhou W, Su B, Tang L, Zhao Y, Wu X, Yin D, Fan M, Zhou C. Dual integrin alphavbeta 3 and NRP-1-Targeting Paramagnetic Liposome for Tumor Early Detection in Magnetic Resonance Imaging. Nanoscale Research Letters. 2018; 13:380. 14.Yin D#, Liu W#, Zeljic K, Lv Q, Wang Z, You M, Men W, Fan M, Cheng W, Wang Z. Failure in Cognitive Suppression of Negative Affect in Adolescents with Generalized Anxiety Disorder. Scientific Reports. 2017; 7:6583. 15.Wen Z, Cheng , Yin D, Sun S, Wang Z, Yu S, Zhang Y, Qiu Z, Du Y. Identification of the Genetic Cause for Childhood Disintegrative Disorder by Whole-Exome Sequencing. Neuroscience Bulletin. 2017; 33:251-254. 16.Yin D, Liu W, Zeljic K, Wang Z, Lv Q, Fan M, Cheng W, Wang Z. Dissociable Changes of Frontal and Parietal Cortices in Inherent Functional Flexibility across the Human Life Span. Journal of Neuroscience. 2016; 36(39):10060 –10074. 17.Zheng X, Sun L, Yin D, Jia J, Zhao Z, Jiang Y, Wang X, Wu J, Gong J, Fan M. The plasticity of intrinsic functional connectivity patterns associated with rehabilitation intervention in chronic stroke patients. Neuroradiology. 2016; 58:417-427 18.Zhao Z, Wang X, Fan M, Yin D, Sun L, Jia J, Tang C, Zheng X, Jiang Y, Wu J, Gong J. Altered Effective Connectivity of the Primary Motor Cortex in Stroke: A Resting-State fMRI Study with Granger Causality Analysis. PLoS One. 2016; 11:e0166210 19.Yan C, Su L, Wang Y, Xu T, Yin D, Fan M, Deng C, Hu Y, Wang Z, Cheung E, Lim K, Chan R. Multivariate Neural Representations of Value during Reward Anticipation and Consummation in the Human Orbitofrontal Cortex. Scientific Reports. 2016; 6:29079 20.Yan C, Wang Y, Su L, Xu T, Yin D, Fan M, Deng C, Wang Z, Lui S, Cheung E, Chan R. Differential mesolimbic and prefrontal alterations during reward anticipation and consummation in positive and negative schizotypy. Psychiatry Research: Neuroimaging. 2016; 254:127-136 21.Liu W#, Yin D#, Cheng W, Fan M, You M, Men W, Zang L, Shi D, Zhang F. Abnormal Functional Connectivity of the Amygdala-Based Network in Resting-State fMRI in Adolescents with Generalized Anxiety Disorder. Medical Science Monitor. 2015; 21: 459-467. 22.Jiang Y, Yin D, Xu D, Men W, Cao R, Li B, Fan M. Investigating microbleeding in cerebral ischemia rats using susceptibility-weighted imaging. Magnetic Resonance Imaging. 2015; 33:102-109. 23.Wang Y, Yan C, Yin D, Fan M, Cheung E, Pantelis C, Chan RC. Neurobiological changes of schizotypy: evidence from both volume-based morphometric analysis and resting-state functional connectivity. Schizophrenia Bulletin. 2015; 41 Suppl 2:S444-454 24.Yin D, Song F, Xu D, Sun L, Men W, Zang L, Yan X, Fan M. Altered topological properties of the cortical motor-related network in patients with subcortical stroke revealed by graph theoretical analysis. Human Brain Mapping. 2014; 35:3343–3359 25.He X, Liu W, Li X, Li Q, Liu F, Rauh VA, Yin D, Bansal R, Duan Y, Kangarlu A, Peterson BS, Xu D. Automated assessment of the quality of diffusion tensor imaging data using color cast of color-encoded fractional anisotropy images. Magnetic Resonance Imaging. 2014;32:446-456 26.Guo W, Li D, Zhu J, Wei X, Men W, Yin D, Fan M, Xu Y. A magnetic nanoparticle stabilized gas containing emulsion for multimodal imaging and triggered drug release. Pharmaceutical Research. 2014; 31:1477–1484 27.Lin Z, Tao J, Gao Y, Yin D, Chen A, Chen L. Analysis of central mechanism of cognitive training on cognitive impairment after stroke: Resting-state functional magnetic resonance imaging study. Journal of International Medical Research. 2014; 42(3) 659–668 28.Yin D, Yan X, Fan M, Hu Y, Men W, Sun L, Song F. Secondary degeneration detected by combining voxel-based morphometry and tract-based spatial statistics in subcortical strokes with different outcomes in hand function. American Journal of Neuroradiology. 2013; 34:1341-1347 29.Yin D#, Luo Y#, Song F, Xu D, Peterson BS, Sun L, Men W, Yan X, Fan M. Functional reorganization associated with outcome in hand function after stroke revealed by regional homogeneity. Neuroradiology. 2013; 55:761-770 30.Dai H, Yin D, Hu C, Morelli JN, Hu S, Yan X, Xu D. Whole-brain voxel-based analysis of diffusion tensor mri parameters in patients with primary open angle glaucoma and correlation with clinical glaucoma stage. Neuroradiology. 2013; 55:233-243 31.Sun L, Yin D, Zhu Y, Fan M, Zang L, Wu Y, Jia J, Bai Y, Zhu B, Hu Y. Cortical reorganization after motor imagery training in chronic stroke patients with severe motor impairment: A longitudinal fmri study. Neuroradiology. 2013; 55:913-925 32.Dai H, Morelli JN, Ai F, Yin D, Hu C, Xu D, Li Y. Resting-state functional mri: Functional connectivity analysis of the visual cortex in primary open-angle glaucoma patients. Human Brain Mapping. 2013; 34:2455-2463 33.Yan X, Zhou M, Ying L, Yin D, Fan M, Yang G, Zhou Y, Song F, Xu D. Evaluation of optimized b-value sampling schemas for diffusion kurtosis imaging with an application to stroke patient data. Computerized Medical Imaging and Graphics. 2013; 37:272-280 34.Men W, Falk D, Sun T, Chen W, Li J, Yin D, Zang L, Fan M. The corpus callosum of albert einstein's brain: Another clue to his high intelligence? Brain. 2013. doi:10.1093/brain/awt252 35.Yin D, Song F, Xu D, Peterson BS, Sun L, Men W, Yan X, Fan M. Patterns in cortical connectivity for determining outcomes in hand function after subcortical stroke. PLoS One. 2012; 7:e52727 36.Song F#, Zhang F#, Yin D#, Hu Y, Fan M, Ni H, Nan X, Cui X, Zhou C, Huang C, Zhao Q, Ma L, Xu Y, Xia Q. Diffusion tensor imaging for predicting hand motor outcome in chronic stroke patients. Journal of International Medical Research. 2012; 40:126-133 | |
研究团队：尹大志、朱恒成、宿凯强、杨旖飞雪 副研究员： 无 助理工程师： 无 博士生： 无 硕士生： 宿凯强、杨旖飞雪 | |
